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Bionic Glue Can Quickly And Effectively Stop Bleeding.

2019/5/17 20:05:00 7484

Biomimetic GlueHemostasis

How can the wound heal quickly?

A team of researchers from the Zhejiang University School of Medicine reported a new kind of hydrogel material that can completely block large artery injury and bleeding from cardiac penetrating wounds in dozens of seconds. The effect of this material has been confirmed in animal experiments, and is expected to be widely applied in clinical practice in the future.

The relevant research results were published in the journal Nature communication 14.

Rapid hemostasis and wound closure are a great challenge in cardiac surgery and macrovascular surgery. There are many deaths due to ineffective control of bleeding every year.

"Ideal adhesives not only have strong adhesion to wet tissue, but also resist high blood pressure and heart beating.

However, there is no material to meet the above requirements. "

Ouyang Hongwei, a correspondence professor and professor of Zhejiang University.

The team designed a gel that mimics the extracellular matrix (a network composed of proteins and other molecules), which can rapidly solidify under ultraviolet light.

In the preliminary animal experiments carried out in the laboratory, the hydrogel could quickly seal the large wound on the liver of pigs. Subsequently, a group of pig surgical operations showed that the hydrogel could also make the penetrating wound of the pig heart quickly shut down and stop bleeding without suture.

It is reported that researchers will conduct further pre clinical studies to assess whether this hydrogel has potential toxicity and ensure that it can be safely used in the future.

The first author of this paper, Zhejiang University, postdoctoral Hong Yi, said the new material is easy to be injected and is easy to use. It has a good application prospect in trauma, rapid hemostasis, open surgery, minimally invasive endoscopic surgery, hemostasis and wound closure.

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