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Orders For Large-Scale Nucleic Acid Detection: Shortage Of Appointment In Some Cities

2021/1/22 13:40:00 0

Orders For Large-Scale Nucleic Acid Detection: Due To The Shortage Of Appointment In Some CitiesThe Third-Party Medical Inspection Institutions Are Arranged Overnight

"I went to three public hospitals to find one that could be tested on the same day. It's really difficult to do nucleic acid testing without making an appointment in advance. I'm going to Hangzhou this Saturday because I have an urgent matter. I'm going to do nucleic acid testing quickly. I'm relieved." On the morning of January 21, an office worker in Nanshan District of Shenzhen City (a pseudonym) told the reporter of the 21st century economic report that "at present, the latest available number has been arranged to January 23. Doctors said the hospital is planning to take the same day's call in response to the surge in demand

Whether the Spring Festival can return home smoothly has become a hot topic recently. In this regard, at the news conference of the national joint prevention and control mechanism held on January 20, Wang Bin, the inspector general of the disease control bureau of the National Health Commission, said, "if it is necessary to return home, the returning personnel must hold a negative nucleic acid test certificate within seven days before they can return home. At the same time, after these returning personnel go back, the local grass-roots government should carry out grid management." It is also pointed out that, regardless of the high, middle and low-risk areas, the cost of nucleic acid detection for returnees should be borne by themselves.

In this regard, the public raised a lot of questions. For example, how to define "returning home"? Province self driving travel, a few hours can go back and forth, do you also want nucleic acid detection? Do you also need nucleic acid detection for the return trip after the festival? Is it necessary to test every 7 days during the Spring Festival? The official wechat official account "healthy China" of the National Health Commission issued an article on the evening of January 20 to answer relevant questions.

The impact of the new regulations on the third-party medical examination industry appeared the next day. In the early trading of January 21, gene testing plates such as Jinyu Medical Co., Ltd. opened higher, Dean diagnostics Rose 14%, Kaipu biology rose more than 10%, and Xilong science, Jinyu medicine, Daan gene and other stocks rose more than 8%. Among them, Jinyu medical opened at 153.01 yuan. As of 09:30 on the same day, the stock rose 10% to 153.12 yuan, closing the limit board.

On January 21, the trading limit of Jinyu Medical Co., Ltd. closed at 153.12 yuan per share, with a total market value of 70.36 billion yuan. Dean diagnostics reported 43.96 yuan per share, up 11.32%. Kaipu biology daily shares 42.68 yuan, up 15.23%, the highest on the day of 43.88 yuan, the total market value of 10.05 billion yuan. Daan gene reported 38.32 yuan per share, up 7.55%. The trading limit of Xilong science closed at 6.17 yuan per share, with a total market value of 3.611 billion yuan.

However, for the third-party medical examination industry, although the new regulations are good for it, there are still some problems.

Is the detection capability adequate?

A few days ago, the work plan for prevention and control of new crown pneumonia in rural areas in winter and spring has deployed the epidemic prevention work of rural areas and returnees. The National Health Commission answered key questions on the evening of January 20, and made it clear that the returnees referred to in the work program refer to those who return to rural areas from other places. It mainly includes: 1) cross provincial returnees; 2) returnees from the cities of medium and high-risk areas in the province (internal personnel in medium and high-risk areas are not mobile in principle); 3) key groups in the province, such as imported cold chain food employees, employees directly contacting imported goods at ports, workers working in isolated places, and employees in transportation vehicles.

Wang Xiuchun, deputy director of the transport service department of the Ministry of transport, previously said that according to the development trend of the epidemic situation at home and abroad, as well as some relevant policies issued by various localities, combined with the ticket pre-sale situation and recent changes in passenger flow, it is estimated that about 1.7 billion passengers will be sent during the National Spring Festival transportation in 2021, with an average daily passenger flow of 40 million, which is more than 40% lower than that in 2019 and 10% higher than that in 2020 More, more pressure on the Spring Festival transportation.

In the face of such a large flow of personnel, relevant testing institutions need to increase the reserves of manpower, equipment and detection reagents in a short period of time, so that they can be used in time.

At the joint prevention and control mechanism conference held by the State Council on January 13, Guo Yanhong, the inspector general of the medical administration bureau of the National Health Commission, introduced the current national nucleic acid detection capacity, saying that there are 8437 medical and health institutions in China that can carry out nucleic acid detection, and the single tube detection capacity reaches 12.55 million per day. As expected, the existing nucleic acid detection capability is still under pressure to meet the demand of Spring Festival transportation.

Moreover, the cost of nucleic acid detection is also a big problem. At present, the cost of detection reagents in most places is 100-200 yuan, and the costs of screening by non-governmental organizations and nucleic acid testing for personal travel are all borne by themselves. Among them, the cost of nucleic acid detection reagents has also been reduced in a few areas. In December 2020, Guangdong will reduce the detection cost to 85 yuan; on January 14, 2021, the maximum price limit of nucleic acid detection projects in Hubei Province will be reduced from 132 yuan per time to 80 yuan; on January 18, 2021, Heilongjiang Province will also reduce the cost of nucleic acid detection from 109 yuan to 80 yuan.

From the public bidding price of nucleic acid diagnostic reagents, the prices in different places are not uniform. The lowest price is 12.9 yuan per person, and there are also 22.3 yuan per person.

However, it is understood that the widely used methods of mixed detection and mixed sampling can effectively reduce the cost of nucleic acid detection and relieve the pressure of detection to a certain extent. It is usually carried out in the ratio of 1:10 or 1:5.

Mixed inspection means that 10 or 5 persons to be tested are sampled separately for each person, but 10 or 5 samples are mixed together as one sample for testing. For mixed sampling, 10 or 5 swabs are put into a sample preservation solution and sent to the laboratory for testing. If the positive result is detected, the single test will be carried out again.

It is worth mentioning that the medical laboratory industry is a typical technology intensive industry. Laboratory personnel with rich business experience are very important to the development of enterprises. However, due to the lack of standardized professional title rating system, the recent work intensity has also increased significantly, and the phenomenon of talent shortage in the industry is serious.

Since the beginning of winter, sporadic cases and localized epidemic outbreaks have appeared in rural areas for the first time. During the Spring Festival transportation, the number of returning people will also increase significantly, and the flow of personnel will increase. In addition, the ability of epidemic prevention and control in rural areas is weak and the prevention and control is difficult, so the transmission risk will be further increased. Different from the first and second tier cities, the resources of nucleic acid detection professionals and equipment are not sufficient in many rural areas, even in cities below the third tier, and the detection ability is still lacking.

The third-party medical examination institutions respond overnight

As soon as the new regulations for returning home during the Spring Festival came out, many medical inspection institutions took measures overnight and launched special nucleic acid detection services.

On the evening of January 20, Jinyu medical published an article on its official wechat public account, saying that orders for nucleic acid detection can be accepted in the official flagship store of e-commerce platform, and individuals can sample at designated sampling points by appointment; teams with more than 30 people can also enjoy door-to-door sampling service. Dean diagnosis also launched a group single appointment, door-to-door service. According to Dean's flagship store on tmall, the advance payment for enterprises with 50-100 employees is 3000 yuan, and that for enterprises with more than 100 people is 5000 yuan.

In addition, hapoulos also launched the online "shopping competition" service, with the slogan of "if the community is close, 100 people can make an appointment for door-to-door sampling, and report within 24 hours". Xu Mingyan, chairman of hapoulos, told reporters that at present, the business of "pincaicai" can cover Shenzhen and its surrounding areas, Tianjin and its surrounding areas and Jiangxi Province.

However, in the situation of "tight time and heavy tasks", whether the third-party medical inspection institutions can take social responsibility while grasping business opportunities and complete tasks with quality and quantity has also become the focus of public attention.

Five days before the new regulations were issued, there was a false report of nucleic acid test results in Longyao County, Xingtai City, Hebei Province.

In recent years, quality control management has gradually attracted the attention of the third-party medical inspection institutions. The whole process of quality control from before, during and after the test is established, covering many elements such as testing environment, methods, talents, reagents, equipment and traceability. Through the implementation of the management responsibilities of each link of the laboratory, the management responsibilities are specified and clarified to ensure that each management is in place 。

The state has also issued relevant policies. In August last year, the medical treatment group of the joint prevention and control mechanism of the State Council organized the formulation of the "Interim Measures for the management of medical laboratory", requiring all localities to strengthen the management of medical laboratory, improve the level of medical examination, ensure the medical quality and medical safety; formulate perfect rules and regulations and process specifications to ensure that the test results are true, accurate, objective and fair, free from improper factors No false or non-conforming inspection report will be issued.

However, Xu Mingyan disclosed to the 21st century economic reporter that although "business opportunities" continue in the industry, in fact, the profits of the whole third-party inspection industry are falling. At present, on the basis of unified regulation and control, the third-party medical inspection institutions are serving with the mentality of half public welfare and half commerce.

Some people in the industry also told reporters of the 21st century economic report that "we should not let the government and the people bear too heavy a burden in order to earn money for fighting the epidemic, but we also need to consider the survival and development of enterprises."

According to the financial report of Jinyu medical in the first quarter of 2020, its operating revenue reached 1.171 billion yuan, with a net profit attributable to its parent company of 47.9101 million yuan, up 13.14% year on year. Although the performance has increased steadily, the relevant person in charge told reporters that the market profit of third-party testing institutions is not as large as that of simple reagent production space, and the cost of nucleic acid detection is relatively high.

According to the semi annual performance report of dangene in 2020, although the company expects the net profit attributable to shareholders of listed companies from January to June 2020 to be 620 million to 800 million yuan, with a year-on-year increase of 924.57% - 1222.03%, but the performance has not much to do with the detection business, mainly due to the new coronavirus nucleic acid detection kit, nucleic acid detection instrument and related consumables developed by Daan gene This is due to a substantial increase in demand.

It can be seen that although the price of the kit used in the new crown nucleic acid detection is not high, the consumables, manpower, transportation, protection of medical and experimental personnel, laboratory construction and hardware maintenance of experimental instruments constitute a huge cost system, which depresses the profits of enterprises.

In addition, the third-party medical examination institutions must keep up with the relevant policies.

Recently, the joint prevention and control mechanism of the State Council issued the notice on further improving the prevention and control of the current epidemic situation of new crown pneumonia, which set a new standard for nucleic acid detection ability in various regions: cities with a permanent population of less than 5 million can complete the detection of all staff within 2 days by coordinating the resources in the province. Cities with a permanent resident population of more than 5 million have the ability to complete full staff testing within 3-5 days by coordinating provincial resources and national support. All localities should have a better understanding of the nucleic acid detection capability, coordinate the efforts of disease control institutions, medical institutions and third-party testing institutions to quickly fill the gaps in personnel, materials and equipment. It is necessary to strengthen the screening of key personnel, carry out nucleic acid testing at least once a week for high-risk groups such as cold chain food employees, regularly carry out nucleic acid sampling test for service employees, and regularly carry out environmental nucleic acid testing for some key places, so as to actively detect the epidemic situation.

 

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